Protein Details: Potassium voltage-gated channel subfamily H member 2

Protein ID

ICDB_Pro_1652

Protein Name

Potassium voltage-gated channel subfamily H member 2

Gene Name

KCNH2; ERG

Organism

Sus scrofa (Pig)

Length

97 amino acids

AlphaFoldDB

AF-Q9TUI4-F1-model_v4.pdb

Function

Pore-forming (alpha) subunit of voltage-gated inwardly rectifying potassium channel. Channel properties are modulated by cAMP and subunit assembly. Mediates the rapidly activating component of the delayed rectifying potassium current in heart (IKr) (By similarity)

Sequence

LLKETEEGSQAPDCGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTAR

PDB Structures

Ligand Binding

1. DICL_CP

2. DICL_Pep

Binding Site

Disease

Location

DOI ID

RefSeq

Feature